{"id":5335,"date":"2021-06-09T12:47:21","date_gmt":"2021-06-09T12:47:21","guid":{"rendered":"https:\/\/aboutsmallruminants.com\/?p=5335"},"modified":"2026-05-13T07:12:42","modified_gmt":"2026-05-13T07:12:42","slug":"efficacia-vaccino-chlamydia-abortus","status":"publish","type":"post","link":"https:\/\/aboutsmallruminants.com\/it\/efficacia-vaccino-chlamydia-abortus\/","title":{"rendered":"Valutazione dell’efficacia dell’ultimo vaccino inattivato immesso in commercio contro chlamydia abortus"},"content":{"rendered":"
Chlamydia abortus<\/em> \u00e8 l’agente eziologico dell’aborto enzootico ovino (AEO), una malattia di grande rilevanza sul piano economico in tutto il mondo. Nel 2019, \u00e8 stato immesso in commercio un nuovo vaccino inattivato contro l’AEO: INMEVA. In quest’articolo, riferiamo i risultati di uno studio pubblicato recentemente sulla prestigiosa rivista scientifica Frontiers in Veterinary Science, che si \u00e8 proposto di valutare l’efficacia e la sicurezza di questo vaccino.
\n<\/strong><\/div>\n

 <\/p>\n

Il patogeno<\/h2>\n

Chlamydia abortus<\/em><\/a> \u00e8 la principale causa di aborto nei piccoli ruminanti<\/strong>. I segni clinici sono: aborto alla fine della gestazione, mortalit\u00e0 neonatale, parto prematuro o nascita di agnelli gracili.<\/p>\n

\u201cChlamydia abortus \u00e8 una delle cause principali di aborto nei piccoli ruminanti in tutto il mondo, con perdite economiche significative\u201d<\/span><\/strong><\/p><\/blockquote>\n

Questa patologia si diffonde facilmente durante l’agnellatura, mantenendo il rischio di infezione<\/strong> nel gregge.<\/p>\n

\"\"<\/a><\/p>\n

 <\/p>\n

Perch\u00e9 \u00e8 stato necessario questo studio?<\/h2>\n

La sicurezza dei vaccini vivi attenuati<\/a> \u00e8 stata recentemente messa in dubbio dalla comunit\u00e0 scientifica<\/a>; \u00e8 stato dimostrato che i vaccini inattivati inducono l’immunit\u00e0 negli ovini<\/strong>, ma la loro efficacia \u00e8 incerta, e che non sono in grado di ridurre lo shedding virale.<\/p>\n

\u201cI vaccini in commercio contro l’AEO hanno evidenziato problemi a livello di sicurezza ed efficacia\u201d<\/span><\/strong><\/p><\/blockquote>\n

Per questo motivo \u00e8 stato condotto questo studio<\/a> che ha valutato l’efficacia e la sicurezza di questo nuovo vaccino inattivato, INMEVA<\/a>.<\/p>\n

 <\/p>\n

Quali sono stati i risultati?<\/h2>\n

Per valutare l’efficacia<\/strong> di questo vaccino, sono stati confrontati i risultati ottenuti su due gruppi di pecore gravide, infettate sperimentalmente con C. abortus<\/em>: un gruppo vaccinato e un gruppo di controllo (non vaccinato). Sono stati confrontati i dati relativi a segni clinici, comportamento, temperatura e peso degli agnelli.<\/p>\n

\"\"<\/a>
Con il nuovo vaccino inattivato, siamo in grado di controllare l’AEO in modo efficace e sicuro.<\/figcaption><\/figure>\n

I risultati hanno evidenziato che nel gruppo vaccinato i segni clinici sono diminuiti del 75% e lo shedding virale del 55% rispetto al gruppo non vaccinato. Inoltre, un effetto positivo \u00e8 stato osservato sull’incremento ponderale degli agnelli<\/strong>.<\/p>\n

\u201cI risultati confermano che INMEVA riduce i segni clinici e lo shedding virale\u201d<\/span><\/strong><\/p><\/blockquote>\n

In termini di sicurezza, non sono state osservate reazioni avverse nel gruppo vaccinato.<\/p>\n

 <\/p>\n

Conclusioni<\/h2>\n

Il vaccino inattivato disponibile in commercio<\/a> INMEVA \u00e8 sicuro e mostra un livello soddisfacente di protezione<\/strong> contro Chlamydia abortus<\/em>.<\/p>\n

Nello studio sono stati osservati i seguenti effetti del vaccino:<\/p>\n

\u25cf Riduzione dei segni clinici a livello riproduttivo.<\/strong>
\n\u25cf Riduzione dello shedding clamidiale.<\/strong>
\n\u25cf Minimizzazione della perdita ponderale negli agnelli.<\/strong>
\n\u25cf Assenza di reazioni avverse.
\n<\/strong><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Chlamydia abortus \u00e8 l’agente eziologico dell’aborto enzootico ovino (AEO), una malattia di grande rilevanza sul piano economico in tutto il mondo. Nel 2019, \u00e8 stato immesso in commercio un nuovo vaccino inattivato contro l’AEO: INMEVA. In quest’articolo, riferiamo i risultati di uno studio pubblicato recentemente sulla prestigiosa rivista scientifica Frontiers in Veterinary Science, che si […]<\/p>\n","protected":false},"author":17,"featured_media":5317,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":{"source_name":"","source_url":"","via_name":"","via_url":"","override_template":"0","override":[{"template":"1","single_blog_custom":"","parallax":"1","fullscreen":"0","layout":"right-sidebar","sidebar":"default-sidebar","second_sidebar":"default-sidebar","sticky_sidebar":"1","share_position":"top","share_float_style":"share-monocrhome","show_share_counter":"1","show_view_counter":"1","show_featured":"1","show_post_meta":"1","show_post_author":"1","show_post_author_image":"1","show_post_date":"1","post_date_format":"default","post_date_format_custom":"Y\/m\/d","show_post_category":"1","show_post_reading_time":"0","post_reading_time_wpm":"300","show_zoom_button":"0","zoom_button_out_step":"2","zoom_button_in_step":"3","show_post_tag":"1","show_prev_next_post":"1","show_popup_post":"1","number_popup_post":"1","show_author_box":"0","show_post_related":"0","show_inline_post_related":"0"}],"override_image_size":"0","image_override":[{"single_post_thumbnail_size":"crop-500","single_post_gallery_size":"crop-500"}],"trending_post":"0","trending_post_position":"meta","trending_post_label":"Trending","sponsored_post":"0","sponsored_post_label":"Sponsored by","sponsored_post_name":"","sponsored_post_url":"","sponsored_post_logo_enable":"0","sponsored_post_logo":"","sponsored_post_desc":""},"jnews_primary_category":{"id":""},"footnotes":""},"categories":[37],"tags":[90],"class_list":["post-5335","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-riproduttivo","tag-restricted"],"yoast_head":"\nEvaluation of a new inactivated vaccine against Ovine Enzootic Abortion<\/title>\n<meta name=\"description\" content=\"This study shows that the inactivated vaccine INMEVA is effective and safe against Ovine Enzootic Abortion. 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