{"id":8008,"date":"2022-10-21T08:29:49","date_gmt":"2022-10-21T08:29:49","guid":{"rendered":"https:\/\/aboutsmallruminants.com\/?p=8008"},"modified":"2022-11-21T08:50:57","modified_gmt":"2022-11-21T08:50:57","slug":"comprendere-chlamydia-abortus-come-si-manifesta-la-malattia","status":"publish","type":"post","link":"https:\/\/aboutsmallruminants.com\/it\/comprendere-chlamydia-abortus-come-si-manifesta-la-malattia\/","title":{"rendered":"Comprendere Chlamydia abortus: come si manifesta la malattia?"},"content":{"rendered":"\t\t
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Chlamydia abortus<\/em> \u00e8 uno dei patogeni che causa i maggiori problemi riproduttivi negli ovini e nei caprini. Sebbene sia il patogeno pi\u00f9 diffuso, ci sono ancora incognite sul suo ciclo. Avere una buona comprensione della malattia \u00e8 di grande importanza per attuare le corrette misure di controllo.<\/p><\/div>

“Schema” di infezione<\/h2>

Quando un gregge viene infettato da C. abortus<\/em><\/strong><\/a>, la malattia si comporta come segue:<\/p>

Primo anno<\/u><\/strong>:<\/strong> di solito si verifica un basso numero<\/strong> di aborti. Solo gli animali che vengono infettati all’inizio della gravidanza abortiscono e diventano una fonte di infezione<\/strong>.<\/p>

Gli animali infetti che non sono gravidi o sono in una fase avanzata della gravidanza (>110 giorni) non mostrano segni, poich\u00e9 Chlamydia rimane latente<\/strong> fino alla gravidanza successiva.<\/p>

Secondo anno<\/u><\/strong>: di solito si verifica un’epidemia o “tempesta di aborti”<\/strong>, poich\u00e9 sono infetti molti pi\u00f9 animali<\/strong> rispetto al primo anno. Questo avviene perch\u00e9 gli animali che hanno abortito l’anno precedente espellevano<\/strong><\/a> Chlamydia, diffondendo l’infezione<\/strong> in tutto il gregge.<\/p>

Inoltre, negli animali con infezione latente, al ripresentarsi di una gravidanza, Chlamydia riattiva il ciclo<\/strong> causando un aborto.<\/p>

Il secondo anno dopo l’infezione da C. abortus si verifica un’epidemia con un tasso di aborti del 20-30%.<\/p><\/blockquote>

Terzo anno<\/u><\/b>: l\u2019infezione si stabilizza e il tasso di aborti \u00e8 generalmente del 5-10% circa. Tuttavia, Chlamydia viene escreta anche nei parti normali, quindi l\u2019infezione continua a diffondersi<\/b>.<\/p>

Anni successivi<\/u><\/strong>: pu\u00f2 verificarsi un’epidemia ogni 3 anni circa<\/strong>, poich\u00e9 gli animali sviluppano un’immunit\u00e0 naturale<\/strong> che li protegge dall’aborto solo per 1-3 anni.<\/p>

\"\"<\/h4>

Fig. 1. Stima (caso ipotetico) dell’evoluzione della % di aborti in un gregge na\u00efve infetto da Chlamydia abortus.<\/em><\/p>

\u00a0<\/h4>

Punto chiave per il controllo<\/h2>

L’escrezione di Chlamydia<\/strong> \u00e8 il fattore che determina la sua diffusione<\/strong> nell’allevamento e la dinamica dell’infezione.<\/p>

Pertanto, il punto chiave per il controllo sar\u00e0 la riduzione dell’escrezione<\/strong>, obiettivo che pu\u00f2 essere raggiunto con la vaccinazione<\/a>.<\/strong><\/p>

I risultati di uno studio mostrano che il vaccino inattivato INMEVA riduce l’escrezione di Chlamydia del 55%.<\/p><\/blockquote>

Vaccinando il gregge<\/strong><\/a> saremo in grado non solo di abbassare il numero di aborti<\/strong> ma anche di ridurre la pressione dell’infezione<\/strong> e proteggere<\/strong> gli animali da nuove infezioni.<\/p>

Conclusioni<\/h2>

\u00c8 importante sapere come si manifesta la malattia per controllarla.<\/p>

Il punto chiave per il controllo di C. abortus \u00e8 la riduzione dell’escrezione<\/strong>, obiettivo che pu\u00f2 essere raggiunto con la vaccinazione<\/strong>.<\/span><\/p>

Articolo scritto da:\u00a0<\/strong>
Tania Per\u00e1lvarez Puerta. Global Product Manager, Small Ruminants Franchise \u2013 HIPRA<\/p>

Bibliografia:<\/strong><\/p>

Montbrau, C. et al., (2020) Evaluation of the Efficacy of a New Commercially Available Inactivated Vaccine Against Ovine Enzootic Abortion. Frontiers in Veterinary Science, 7(593)<\/p>

Milne, E. et al., (2008) Epidemiological modelling of chlamydial abortion in sheep flocks. Veterinary Microbiology 135 (2009) 128\u2013133<\/p>

Longbottom, D. et al., (2013) Intranasal Infection with Chlamydia abortus induces dose-dependent latency and abortion in sheep. Plos One 8(2)<\/p>

Livingstone, M. (2008) Molecular detection of Chlamydophila abortus in post-abortion sheep at oestrus and subsequent lambing. Veterinary Microbiology 135 (2009) 134\u2013141<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Chlamydia abortus \u00e8 uno dei patogeni che causa i maggiori problemi riproduttivi negli ovini e nei caprini. Sebbene sia il patogeno pi\u00f9 diffuso, ci sono ancora incognite sul suo ciclo. Avere una buona comprensione della malattia \u00e8 di grande importanza per attuare le corrette misure di controllo. <\/p>\n","protected":false},"author":10,"featured_media":8013,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[37],"tags":[],"class_list":["post-8008","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-riproduttivo"],"yoast_head":"\nComprendere Chlamydia abortus | Small Ruminants<\/title>\n<meta name=\"description\" content=\"Conoscere un'infezione da Chlamydia abortus ci aiuter\u00e0 ad attuare misure di controllo\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/aboutsmallruminants.com\/it\/comprendere-chlamydia-abortus-come-si-manifesta-la-malattia\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta 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